COVID Research & Resources Group


Aerosol References and comments

  • 1.  Aerosol References and comments

    Posted 07-15-2020 17:03
    Leonid Turkevich kindly gave me the following references on aerosols.  He is not posting them himself because of the hassle of dealing with the red tape of posting a US Government Disclaimer.

    "You ask about aerosols references.

    A good introductory text is W.A. Hinds, Aerosol Technology—it’s a good way to get a broad overview.

    A more encyclopedic book is Kulkarni, Baron, Willeke, Aerosol Measurement (3rd edition of the earlier Baron & Willeke), which has review articles on specific topics.

    In terms of viral load, an aerosol study makes sense if you are looking at enclosed indoor air.

    However, once the virus enters the body, it quickly is adsorbed onto biological surfaces, so I am not sure where one would go with an aerosol treatment."

    He also adds:
    "There are probably several routes—inhalation being the most commonly considered—but I would not discount entry via the eyes.

    Droplet-carried or direct virus aerosol will have different penetrations and deposition into the lungs (lots of work on lung penetration models).

    My own recent research has focused on asbestos (larger particles and very different geometry).

    Regardless of whether it is droplet-carried or direct virus aerosol, I would expect rather rapid adsorption onto lung surface cells (where in the lung depends on the transport mechanism)—and then for biological processes to take over.

    A major difference between indoor air and the lungs is humidity (the lungs are very moist)."

    Wayne Saslow
    Texas A&M Univ
    College Station TX